Molecular methods for assessment of non-covalent metallodrug–DNA interactions 

Chem. Soc. Rev. | 2019, Advance Article

A. Kellett, Z. Molphy, C. Slator, V. McKee, N. Farrell


Polypyridyl‐Based Copper Phenanthrene Complexes: A New Type of Stabilized Artificial Chemical Nuclease

Chemistry A European Journal | 2019, 25 (1)

N. Fantoni, Z. Molphy, C. Slator, G. Menounou, G. Toniolo, G. Mitrikas, V. McKee, C. Chatgilialoglu, A. Kellett


Efficient DNA Condensation by a C3‐Symmetric Codeine Scaffold

ChemPlusChem | 2019, vol. 84, issue 1

N. McStay, A. Reilly, N. Gathergood, A. Kellett


[Cu(TPMA)(Phen)](ClO4)2: Metallodrug Nanocontainer Delivery and Membrane Lipidomics of a Neuroblastoma Cell Line Coupled with a Liposome Biomimetic Model Focusing on Fatty Acid Reactivity

ACS Omega | 2018, 3 (11)

G. Toniolo, M. Louka, G. Menounou, N. Fantoni, G. Mitrikas, E. Efthimiadou, A. Masi, M. Bortolotti, L. Polito, A. Bolognesi, A. Kellett, C. Ferreri, C. Chatgilialoglu


Innovative DNA-Targeted Metallo-prodrug Strategy Combining Histone Deacetylase Inhibition with Oxidative Stress​

Mol. Pharmaceutics | 2018, 15 (11)

T.J.P. McGivern, C. Slator, A. Kellett, C.J. Marmion


Fluorogenic thiazole orange TOTFO probes stabilise parallel DNA triplexes at pH 7 and above

Chem. Sci | 2018, 9

S. Walsh, A. El-Sagheer, T. Brown


Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic DNA Functionalization through Copper-Catalyzed Alkyne–Azide 1,3-Dipolar Cycloaddition

Org. Lett. | 2018, 20 (13)

A. Panattoni, R. Pohl, M. Hocek


2‐Allyl‐ and Propargylamino‐dATPs for Site‐Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA

Chemistry A European Journal | 2018, 24 (56)

J. Matyasovsky, R. Pohl, M. Hocek


Brightly Fluorescent 2′-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry

Bioconjugate Chem.| 2018, 29(11)

G. Guixens-Gallardo, Z. Zawada, J. Matyasovsky, D. Dziuba, R. Pohl, T. Kraus, M. Hocek


A Click‐Chemistry Linked 2′3′‐cGAMP Analogue

Chemistry A European Journal | 2018, Hot Topic: Click Chemistry

C. Dialer, S. Stazzoni, D. Drexler, F. Müller, S. Veth, A. Pichler, H. Okamura, G. Witte, K-P. Hopfner, T. Carell


Trans Lipid Library: Synthesis of Docosahexaenoic Acid (DHA) Monotrans Isomers and Regioisomer Identification in DHA-Containing Supplements

Chem. Res. Toxicol. | 2018, 31 (3)

G. Menounou, G. Giacometti, R. Scanferlato, P. Dambruoso, A. Sansone, I. Tueros, J. Amezaga, C. Chatgilialoglu, C. Ferreri


Development of multi-layered and multi-sensitive polymeric nanocontainers for cancer therapy: in vitro evaluation

Nature Scientific Reports | 2018, 8

G. Toniolo, E. Efthimiadou, G. Kordas, C. Chatgilialoglu


Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures

Chem. Commun. | 2018, 54

I. Manuguerra, S. Croce, A.H. El-Sagheer, A. Krissanapasit, T. Brown, K.V. Gothelf, A. Manetto


Genome Engineering with Synthetic Copper Nucleases

Synlett | 2018, 26/19

A. Kellett, N. Fantoni and T. Lauria


Altered Red Blood Cell Membrane Fatty Acid Profile in Cancer Patients

Nutrients | 2018, 10(12)

J. Amezaga, S. Arranz, A. Urruticoechea, G. Ugartemendia, A. Larraioz, M. Louka, M. Uriarte, C. Ferreri, I. Tueros


Stimuli-responsive biopolymer nanocarriers for drug delivery applications

Woodhead Publishing Series in Biomaterials | 2018, 1st edition

E. Efthimiadou, M. Theodosiou, G. Toniolo, N. Abu-Thabit


Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination

Nucleic Acids Research | 2018, 46 (6)

C. Slator, Z. Molphy, V. McKee, C. Long, T. Brown, A. Kellett


A Sulfoxide‐Based Isobaric Labelling Reagent for Accurate Quantitative Mass Spectrometry

Angewandte Chemie International Edition | 2018, 57 (11)

M. Stadlmeier, J. Bogena, M. Wallner, M. Wühr, T. Carell


High predictive values of RBC membrane-based diagnostics by biophotonics in an integrated approach for Autism Spectrum Disorders

Scientific Report | 2017, 7

G. Giacometti , A. Sansone , C. Marzetti , E. Spyratou , A. Georgakilas , C. Chatgilialoglu , M. Marini , P. M. Abruzzo, A. Bolotta , A. Ghezzo , R. Minguzzi , A. Posar , P. Visconti and C. Ferreri.


Fluorous-tag assisted synthesis of bile acid–bisphosphonate conjugates via orthogonal click reactions: an access to potential anti-resorption bone drugs

Organic & Biomolecular Chemistry | 2017, 22

C. Massarenti, O. Bortolini, G. Fantin, D. Cristofaro, D. Ragno, D. Perrone, E. Marchesi, G. Toniolo, A. Massi


Fatty acids in membranes as homeostatic, metabolic and nutritional biomarkers: recent advancements in analytics and diagnostics

Diagnostics | 2017, 7/1

C. Ferreri, A. Masi, A. Sansone, G. Giacometti, A.V. Larocca, G. Menounou, R. Scanferlato, S. Tortorella, D. Rota, M. Conti, S. Deplano, M. Louka, A.R. Maranini, A. Salati, V. Sunda, C. Chatgilialoglu


Dendrimer-Based Signal Amplification of Click-Labelled DNA in Situ

ChemBioChem | 2017, 18

N. Raddaoui, S. Stazzoni, L. Möckl, B. Viverge, F. Geiger, H. Engelke, C. Bräuchle and T. Carell


Synthesis of RNA Containing 5-Hydroxymethyl-, 5-Formyl-, and 5-Carboxycytidine

Chemistry - A European Journal | 2017, 23(63)

I. Michaelides, N. Tago, B. Viverge and T. Carell


Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells

Biochimica et Biophysica Acta (BBA)-Biomembranes| 2017, 1859/10

P. Prasinou, I. Dafnis, G. Giacometti, C. Ferreri, A. Chroni and C. Chatgilialoglu


trans-Double Bond-Containing Liposomes as Potential Carriers for Drug Delivery

Molecules | 2017, 22/12

G. Giacometti, M. Marini, K. Papadopoulos, C. Ferreri and C. Chatgilialoglu


Triggering autophagic cell death with a di-manganese(II) developmental therapeutic

Redox Biology | 2017, 12

C. Slator, Z. Molphy, V. McKee, A. Kellett


Opioid architectures as new DNA binding molecules

Symmetry | 2017, 28 (2)

N. McStay, Z. Molphy, N. Gathergood, A. Kellett


C3-symmetric opioid scaffolds are pH-responsive DNA condensation agents

Nucleic Acids Research | 2017, 45 (2)

N. McStay, Z. Molphy, A. Coughlan, A. Cafolla, V. McKee, N. Gathergood, A. Kellett


2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove

Angewandte Chemie International Edition | 2016, 55/51

J. Matyašovský, P. Perlíková, V. Malnuit, R. Pohl, M. Hocek


5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs

ACS Chemical Biology | 2016, in press

H. Cahová, A. Panattoni, P. Kielkowski, J. Fanfrlík and M. Hocek.


Building up spectral libraries for mapping erythrocytes by hyperspectral dark field microscopy

Biomedical Spectroscopy and Imaging | 2016, 5/2

M. Conti, R. Scanferlato, M. Louka, A. Sansone, C. Marzetti and C. Ferreri.


Hexadecenoic Fatty Acid Isomers in Human Blood Lipids and Their Relevance for the Interpretation of Lipidomic Profiles

PLoS One | 2016, 11/4

A. Sansone, E. Tolika, M. Louka, V. Sunda, S. Deplano, M. Melchiorre, D. Anagnostopoulos, C. Chatgilialoglu, C. Formisano, R. Di Micco, MR. Faraone Mennella and C. Ferreri.


Radical-induced purine lesion formation is dependent on DNA helical topology

Free Radical Research | 2016, 50

M. Terzidis, A. Prisecaru, Z. Molphy, N. Barron, A. Randazzo, E. Dumont, M. Krokidis, A. Kellett, C. Chatgilialoglu


Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions

Chemical Science | 2016, 7/9

D. Dziuba, P. Pospíšil, J. Matyašovský, J. Brynda, D. Nachtigallová, L. Rulíšek, R. Pohl, M. Hof and M. Hocek.


5-Formylcytosin ist vermutlich eine semipermanente Base an definierten Genompositionen

English version: 5-Formylcytosine Could Be a Semipermanent Base in Specific Genome Sites

Angewandte Chemie (Int. Ed.) | 2016, 128/39

M. Su, A. Kirchner, S. Stazzoni, M. Müller, M. Wagner, A. Schroeder and T. Carell.


Protein engineering with artificial chemical nucleases

Chem. Commun. | 2015, 51/65

R. Larragy, J. Fitzgerald, A. Prisecaru, V. McKee, P. Leonard, A. Kellett


[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Michochondrial Dysfunction

ACS Chemical Biology | 2015, 11/1

C. Slator, N. Barron, O. Howe and A. Kellett.


Orchestrating the Biosynthesis of an Unnatural Pyrrolysine Amino Acid for Its Direct Incorporation into Proteins Inside Living Cells

Chemistry - A European Journal | 2015, 21(21) 

M. Ehrlich, M.J. Gattner, B. Viverge, J. Bretzler, D. Eisen, M. Stadlmeier, M. Vrabel, T. Carell.