Prof. Jean Cadet is involved in research activities that deal with various aspects of the chemistry and biochemistry of oxidatively generated and photo-induced damage to DNA. He is the author or co-author of 560 publications consisting of more than 500 original contributions to peer-reviewed journals and about 60 book chapters.
Dr. Andreas Houben
Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung, DE: Head of the research group ‘Chromosome Structure and Function’
PD Dr. Andreas Houben will use his experience in the field to help the development of the project. His research group is very interested to employ novel fluorogenic detector molecules that can monitor the presence of epigenetic base modifications in highly parallel PCR matrixes. PD Dr. Andreas Houben has authored or co-authored 166 publications.
Prof. John M. Kelly
Trinity College Dublin, School of Chemistry, IE: Professor of Chemistry (retd); Fellow Emeritus
Prof. John M. Kelly will support the ClickGene team with his expertise. One of his research interests has been in studying the interaction of photo-activable metal complexes with DNA and targeting photo-oxidation to particular sequences in DNA.
Prof. Shlomo Sasson
The Hebrew University of Jerusalem, The Institute for Drug Research, Department of Pharmacology, Faculty of Medicine, IL: Professor of Pharmacology, Adolf D. and Horty Storch Chair in Pharmacutical Sciencies
Prof. Schlomo Sasson is an expert in the regulation of metabolism, from gene function to cellular complex interactions. He will contribute to the mission of the ClickGene project in all aspects related to genomic alterations and developments of tools to identify and further use them for advanced analysis and development of new methods for their detection and manipulation.
Prof. Jesper Wengel has a background in the area of nucleic acid chemical biology in which he has published more than 300 papers.
K. Barry Sharpless
The Scripps Research Institute (TSRI), Department of Chemistry, The K. Barry Sharpless Lab, US: W. M. Keck Professor of Chemistry
Karl Barry Sharpless won a half-share of the 2001 Nobel Prize in Chemistry. He won the award for his work on chirally catalysed oxidation reactions. Currently he is involved in the new field of click-chemistry.