4th Network Meeting – University of Oxford

PIs and ESRs were reunited from 19 - 21 March 2018 for the third Annual ClickGene Meeting in Oriel College at the University of Oxford (UOXF). Organised by the ClickGene partners UOXF and ATDBio, the annual meeting included workshops, industry and laboratory visits, keynote lectures and ESR presentations.

On the first day, Dr. Jeanette Müller from accelopment AG provided the ESRs with an expert training session on European Grant Application Writing. ESRs were informed about existing EU funding opportunities for young researchers and different steps related to proposal writing. In the afternoon, ESRs had the opportunity to visit the premises of the companies ATDBio Ltd. and Oxford Nanopore Technologies in the Oxford Science Park and they also had the opportunity to visit the research laboratories of Prof. Tom Brown in UOXF.

During the second day, ESRs, PIs and others attended nine cutting-edge lectures by ClickGene PIs and researchers from the UOXF as follows:

Tom Brown, Department of Chemistry, UOXF

“Clicking DNA”

Chrys Chatgilialoglu, CNR

“Our radical approach to biomimetic chemistry.”

Andrew Kellett, Dublin City University

“Molecular Methods for Probing Non-Covalent Metallodrug-DNA Interactions”

Rebecca Andrews, Department of Physics, UOXF

“A single-molecule sequencing method based on DNA binding”

Jonathan Doye, Department of Chemistry, UOXF

“Coarse-grained modelling of DNA”

Graham McClorey, Department of Physiology, Anatomy and Genetics, UOXF

“Cell-Penetrating peptides to enhance oligonucleotide delivery”

Andrew Turberfield, Department of Physics, UOXF

“Molecular machinery from DNA”

Jack Hardwick, Department of Chemistry, UOXF

“F-DNA: A new form of the DNA Double Helix”

Thomas Carell, LMU Munich

“DNA bases beyond Watson and Crick”

On the third and last day, each ESR presented recent advancements in their research projects with the other ESRs and the ClickGene PIs. The ClickGene coordinator Andrew Kellett held a presentation on the status of the ClickGene project, in its last months before completion. A board meeting reuniting PIs and ESR representatives put an end to this 3-day event.

The next network meeting will take place in Dublin, Ireland by the end of the year. Information will follow in due time.

ClickGene PIs and ESRs attend Symposium on Chemistry of Nucleic Acid Components

Most of the ClickGene PIs and ESRs will be attending the 17th Symposium on Chemistry of Nucleic Acid Components (SCNAC) in Český Krumlov, Czech Republic, held in June of this year. Last year’s event attracted more than 150 participants from 21 countries. The programme consists of 10 plenary lectures, 4 "Emerging young investigator" invited lectures, ca. 40 short oral presentations and a poster session.

Supervisor Michal Hocek to chair the symposium

Michal Hocek, supervisor of two ESRs for ClickGene, is the chairman of the SCNAC symposium. Michal’s main research areas include the chemistry of nucleobases, nucleosides, nucleotides and nucleic acids and his ESRs are studying in the area of genome editing and gene knockout.

Invited speakers

The list of invited speakers includes Thomas Carell of the Ludwig-Maximilians-University Munich, Germany. Thomas is, like Michal, the supervisor of two ESRs for the ClickGene project. Additionally, he is the lead of WP1 Materials for Genome Editing. Other speakers include Cynthia Burrows from the University of Utah, Kurt Vesterager Gothelf from the Interdisciplinary Nanoscience Center, Aarhus University and Andreas Marx from the University of Konstanz. The full list of plenary invited speakers is available on the SNAC website.

How to attend

The registration for the event is open and available on the SCNAC website. Due to limited capacity of the venue, the registration will be restricted to ca. 150 regular participants.

Mid-Term Meeting this winter

Planning for the ClickGene Mid-Term Meeting is underway and progress is looking good. We will be hoping to avoid the freezing weather by holding it in Bologna, Italy from the 29th November to the 1st December. The participants are expected to arrive on the 28th November and the first day of work will start the next morning. On the first day the Programme Network Meeting will be held. This includes an update of the project status by the coordinator and updates on the individual Work Packages by their respective leaders. Following that Jeanette Müller will advise the attendees on the requirements, expectations and best practices. Before lunch the first ESRs (Early Stage Researchers) will give an update on their work progress – the other ESRs will do the same after lunch and in the afternoon. Later in the day there will be a Management Board meeting.

On the second day the Technical Review Meeting will take place. The morning and early afternoon will mainly be filled with individual reports by the ESRs and the coordinator. Later in the afternoon the fellows will be holding individual meetings with the REA and a reviewer to discuss their experience within the network.

The final day is reserved for a workshop held by baseclick GmbH. There will be more information available in the Training Programme in due time.

ClickGene Webinar: Research Progress

There is an update concerning the ClickGene Webinar, that will take place on the 20th January 2016. The Webinar will be organised by ACCEL and will be led by Dr. Andrew Kellett and Dr. Jeanette Müller both of whom will also welcome the participants to the Webinar an deliver a short introduction.
The Webinar will give the participants an overview of WP1 (by Prof. Thomas Carell), WP2 (by Prof. Chrys Chatgilialoglu), WP3 (Prof. Carla Ferreri) and WP4 (by Dr. Niall Barron) and will dive into the individual projects in more detail. The ESRs will describe their individual projects persoanlly.

ClickGene Project Start

The ClickGene Project started at 1st January 2015. The project wil be coordinated by Dr Andrew Kellet of the Dublin City University. 
The project will provide training for 14 PhD students in the next 4 years.

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